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  2. प्रो. एस. मजूमदार

Prof. Swapan Majumdar

Professor
Date of Birth : 13/03/1968
Contact Numbers : 0381-237-9070 (office)
+91- 9436124464 (M)
E-mails : smajumdar[at]tripurauniv.ac.in
swamajumdar[at]hotmail.com
swamajumdar[at]gmail.com
Academic Qualifications : : M.Sc., Ph.D.
Topics Taught : Organic chemistry: Aromaticity; Addition-Elimination reactions; reactive intermediates involved in organic synthesis; reagents in organic synthesis; carbohydrates; amino acids, peptides, proteins; various chromatographic techniques; supramolecular and nano chemistry; organic photochemistry; organometallics; heterocyclic chemistry, macrocyclic compounds and their synthesis; prostaglandins; antibiotics. Synthetic strategies; methodologies in organic synthesis; asymmetric synthesis.

Patents

  1. An improved process for the preparation of optically pure chiral cyclic amines. Inventor: Swapan Majumdar and Anup Bhattacharjya, Indian Patent No. 1135/del/97
  2. A process for preparation of clay mineral hybrid. Inventor: Prof. S. A. Hussain, Prof. D. Bhattacharjee and Prof. S. Majumdar, patent granted by Govt. of Australia with No. 2021104639, Dated: 28/07/2021
  3. A Device For Fabricating Indole Derived Films To Obtain Resistive Switching Module. Inventor: Prof. S. Majumdar, Prof. D. Bhattacharjee, Prof. P. K.Paul, Prof. S. A.Hussain, patent granted by Govt. of Germany with patent No. 20 2022 103 887, Dated: 16/08/2022

Publications (Year Wise) :

Year Title of paper / book Name of Journal, Vol. Pages Publisher
2023 Water-SDS-Ionic liquid combo catalytic system for the synthesis of highly functionalized pyrano-chromene derivatives and their ability to inhibit the main protease of SARS-CoV-2. ChemistrySelect, 2023, 8, e202300007 European Chemical Societies Publishing
Ecofriendly Approach for the Large-Scale Synthesis of 4-Unsubstituted Coumarin-3-carboxylic Acids from o-Hydroxy-araldehydes with Meldrum’s Acid in the Water-SDS Micellar System. ChemistrySelect, 2023, 8, e202204128 European Chemical Societies Publishing
2022 Design and synthesis of bis-coumarinylmethanes from 4-hydroxy-coumarin and aldehydes catalyzed by Amberlyst 15 via dual C-C coupling: Introducing coumarin based thin film organic nano-materials for memory devices. Res. Chem. Intermed. 2022, 48, 4963–4985. Springer Nature
An Elegant Approach for Selective Syntheses of 2-Substituted Benzimidazoles at Room Temperature using Ag Nanoparticles as Activator: Effect of Solvent on the Selectivity. Can. J. Chem. 2022, 100, 697-703. Canadian Science Publishing
Expedient approach for trans-esterification of -keto esters under solvent free condition using silica supported boric acid (SiO2-H3BO3) as recyclable catalyst. RSC Adv., 2022, 12, 21493-21502. Royal Society of Chemisty
Complementary Resistive Switching behaviour in tetraindolyl derivative based memory device. Langmuir 2022, 38, 9229-9238. American Chemical Society
Nontraditional Redox Active Aliphatic Luminescent Polymer for Ratiometric pH Sensing and Sensing-Removal-Reduction of Cu(II): Strategic Optimisation of Composition. Macromol. Rapid Commun, 2022, 2200317 Wiley
Dual activation of carboxylic acid functionality by protic ionic liquid: Solvent and metal free strategy for selective esterification of alcohols and acylation of aromatic amines. ChemistrySelect, 2022, 7, e202200937. European Chemical Societies Publishing
Dual activation of carboxylic acid functionality by protic ionic liquid: Solvent and metal free strategy for selective esterification of alcohols and acylation of aromatic amines. Kamal Das and Swapan Majumdar ChemistrySelect (in press, doi.org/10. 1002/slct.202200937 Wiley
Ratiometric pH Sensing, Photophysics, and Cell Imaging of Nonaromatic Light-Emitting Polymer. ACS Appl. Bio Mater., 5, 2990–3005. ACS
Design, synthesis and docking study of Vortioxetine derivatives as a SARS-CoV-2 main protease inhibitor DARU J Phar Sci., 30, 139-152. Springer
Base and metal free true recyclable medium for Knoevenagel condensation reaction in SDS-ionic liquid-aqueous miceller composite system Results in Chemistry 4, 100294 Elsevier
2021 Resistive switching of tetraindolyl derivative in ultrathin films: A potential candidate for non-volatile memory applications Langmuir 2021, 37, 4449−4459 ACS
Bis-indolylation of aldehydes and ketones using silica supported FeCl3: A Molecular docking studies of bisindoles by targeting SARS-CoV-2 main protease binding site RSC Adv., 11, 30827-30839 RSC
Polydiacetylenes-N-1-Hexdecyl Imidazole Mixed Film and its Application towards Sensing of Volatile Organic Compounds (VOCs), Gasoline and Pollution Level in Car Exhaust J. Phys. Chem. C, 125, 15976−15986 ACS
7-Alkoxy appended coumarin derivatives: Synthesis, photo-physical properties, aggregation behaviours and current–voltage (I-V) characteristic studies on thin films RSC Adv., 11, 10212-10223 RSC
2020 A Task-Specific Ionic-Liquid-Mediated Solvent-Free Protocol for Direct Access to DimethylAcetal Protected Benzimidazole2-Carboxaldehydes SynOpen, 4, 85-89 THIEME
Metal-Free Indole−Phenacyl Bromide Cyclization: A Regioselective Synthesis of 3,5-Diarylcarbazoles J Org Chem., 85, 13272−13279 ACS
Self-standing films of tetraindolyl derivative and saponite clay mineral with reversible colour switching properties J. Phy. Chem. Solids, 144, 109487 (7 pages) Elsevier
2019 Discovery of novel potential selective HDAC8 inhibitors by combine ligand-based, structurebased virtual screening and in-vitro biological evaluation Scientific Reports, 9, 171174 Nature
Effect of Functional Group on Electrical Switching Behaviour of an Imidazole Derivative in Langmuir-Blodgett Film ChemistrySelect4, 9065 Wiley
BMIm[OH] catalyzed rapid, mild and improved protocol for the synthesis of 3-hydroxy-3-(nitroalkyl)indolin-2-one derivatives in water ChemistrySelect, 4, 1841 Wiley
2018 An efficient strategy for N-alkylation of benzimidazoles/ imidazoles in SDS-aqueous basic medium and N-alkylation induced ring opening of benzimidazoles Tetrahedron 74, 5932 Elsevier
Synthesis of some new chrysin derivatives and their biological assessment as antibacterial, antibiofilm and antifungal agent. Asian J. Chem., 30, 21167 Asian Publication Corporation
Study of an Imidazole Derivative Mixed with Fatty Acid at Air-Water Interface and in Ultrathin Films Materials Today, 5, 2287 Elsevier
2017 Study of compression induced supramolecular nanostructures of an imidazole derivative by Langmuir-Blodgett technique. Langmuir, 33, 8383 American Chemical Society
Synthesis of macrocyclic conjugated pseudo -disacharides via nitrile oxide cycloaddition: alkenyl chain length controlled unprecedented formation of di-oxa heterocycles from monosacharides Tetrahedron, 73, 3139 Elsevier
Silica-ferric chloride (SiO2-FeCl3) catalyzed selective synthesis of 2-substituted benzimidazole through Csp2-Csp3 bond cleavage of β -ketoester/amide. Synfacts, 13, 111 Thieme
Copper nanoparticles catalyzed N-H functionalization: an efficient solvent-free N-tert-butyloxycarbonylation strategy. Tetrahedron Letts., 58, 629 Elsevier
Amberlite IR 120H+ Catalyzed N-C/C-N Coupled Cylization Strategy to Give Imidazoles: Design and Fabrication of Organic Nanomaterial with AFM Imaging. ChemistrySelect 2, 241. Wiley
2016 Silica-ferric chloride (SiO2-FeCl3) catalyzedselective synthesis of 2-substituted benzimidazole through Csp2-Csp3 bond cleavage of β-ketoester/amide. S. Majumdar Tetrahedron Letters, 57, 4595. Elsevier
Selective exploitation of acetoacetate carbonyl groups using imidazolium based ionic liquids: Synthesis of valuable 3-oxo-amides and substituted benzimidazoles. Tetrahedron Letts., 57, 3298 Elsevier
A combined pharmacophore modeling, 3D QSAR, virtual screening, molecular docking, and ADME studies to identify potential HDAC8 inhibitors Med Chem Res 25, 2434 Springer
Anion Dependent Imidazolium Protic Ionic Liquid Catalyzed Solvent-Free General Strategy for Chemoselective Fmoc and Cbz Protection of Amines and Their Chiral Analogues ChemistrySelect 1, 2668 Wiley
2015 Identification of potent histone deacetylase 8 inhibitors using pharmacophore-based virtual screening, three-dimensional quantitative structure–activity relationship, and docking study Res. Reports Med. Chem. 5, 21-39 Dove Press
Phthalate tethered strategy: carbohydrate nitrile oxide cycloaddition to 12-15 member chiral macrocycles with alkenyl chain length controlled orientation of bridged isoxazolines RSC Advances, 5, 106289 Royal Society of Chemistry
Grindstone chemistry: protic ionic liquid-substrate tuned green synthesis of 1,2-disubstituted and 2-substituted benzimidazoles with outstanding selectivity RSC Advances, 5, 51012 Royal Society of Chemistry
Enediynyl Peptides and Iso-coumarinyl Methyl Sulphones as Inhibitors of Proprotein Conver-tases PCSK8/SKI-1/S1P and PCSK4/PC4: Design, Synthesis and Biological Evaluations. Bioorg. Med. Chem. Letters, 25, 2225 Elsevier
General solvent-free ionic liquid catalyzed C-N/C-C coupled cyclization to diverse dihydropyrimidinones and new organic materials: Langmuir-Blodgett film study RSC Advances, 5, 24681 Royal Society of Chemistry
A protic ionic liquid catalyzed strategy for selective hydrolytic cleavage of tert-butyloxycarbonyl amine (N-Boc) RSC Advances, 5, 3200 Royal Society of Chemistry
2014 General solvent-free highly selective N-tert-butyloxycarbonylation strategy using protic ionic liquid as an efficient catalyst RSC Advances, 4, 24544 Royal Society of Chemistry
Activation of 1, 3-dioxolane by protic ionic liquid in aqueous media: A green strategy for the selective cleavage of acetals and ketals RSC Advances, 2014, 4, 16497 Royal Society of Chemistry
2013 Dynamic Cell Patterning of photoresponsive hyaluronic acid hydrogels J. Bio. Med. Res. Part A, 102, 381 Wiley
Formylation of amines catalysed by protic ionic liquids under solvent-free condition Tetrahedron Letters, 54, 262 Elsevier
Comparative analysis and modeling of photo-caged Arg-Gly-Asp Ser-(RGDS) peptides for cell patterning. J. Biomed. Mater. Res.: Part A, 101A: 787 Wiley
2012 Asymmetric Intramolecular Conjugate Addition of α-Amino Acid Derivatives via Racemization-Free Equilibrium of Intermediary Chiral Enolates. Heterocycles 86, 1483 The Japan Institute of Heterocyclic Chemistry
2011 Novel Circular, Cyclic and Acyclic ψ(CH2O) Containing Peptide Inhibitors of SKI-1/S1P: Synthesis, Kinetic and Biochemical Evaluations. Curr. Med. Chem., 18, 2770 Bentham Science
In Vitro Assay for Protease Activity of Proprotein Convertase Subtillisin Kexins (PCSKs): An Overall Review of Existing and New Methodologies. Methods in Mol. Biology, Vol. 768, 127 Chapter in a book
2010 Insights into the origins of Configurational Stability of Axially Chiral Biaryl Amines with an Intramolecular N–H-N Hydrogen Bond. J. Org. Chem., 75, 5031 American Chemical Society
Proprotein Convertase Inhibitory Activities of Flavonoids Isolated from Oroxylum indicum. Curr. Med. Chem., 17, 2049 Bentham Science
Hydrogel cell patterning incorporating photocaged RGDS peptides Biomedical Microdevice , 12, 555 Springer
2009 Novel Axially Chiral Binaphthyl Surrogates with an inner N-H-N Hydrogen bond J. Am. Chem. Soc., 131, 54-55. American Chemical Society
2006 Synthesis of Chiral 1, 2-Dihydropyridines and 2, 3, 4-Trisubstituted Pyridines from α-Amino Acids. Heterocycles 68, 2571 The Japan Institute of Heterocyclic Chemistry
2005 Intramolecular Asymmetric Conjugate Addition of Enolates with Dynamic Chirality: A Novel Route to Highly Substituted Chiral Cyclic α-Amino Acid Derivatives. Org. & Biomol. Chem. 3, 1609 Royal Society of Chemistry
2004 Stereoselective Synthesis and Reactivity of Dienyl Zirconocene Derivatives. Synthesis 2411 Thieme
New Regio-, Stereo-, Diastereo-, and enantioselective One-Pot Reactions Mediated by Organometallic Derivatives. Pure and Appl. Chem. 76517 International Union of Pure and Applied Chemistry
2003 Stereoselective Preparation of Dienyl Zirconocene complexes via a Tendem Allylic C-H Bond Activation-Elimination Sequence. J. Am. Chem. Soc., 125, 13258 American Chemical Society
Asymmetric Cyclisation via Memory of Chirality: A Concise Access to Cyclic Amino Acids with a Quaternary Stereocenter. J. Am. Chem. Soc., 125, 13012 American Chemical Society
2002 New preparation of sp2 organometallic derivatives. Synthesis 2473 Thieme
New Approach to the Stereoselective Synthesis of Metalated Dienes via an Isomerization-Elimination Sequence. J. Am. Chem. Soc., 124, 10282 American Chemical Society
Catalytic Asymmetric and Stereoselective Synthesis of Vinylcyclopropanes. Synlett, 423. Thieme
2000 Thiourea: A Novel Cleaving Agent for 1, 3-Dioxolanes. Chem. & Eng. News, 2000, 78, 91 American Chemical Society
Synthesis of Chiral 10, 11 and 12-Membered Nitrogen and Oxygen Heterocycles by Intramolecular Nitrile Oxide Cycloaddition of Tethered N-and O-Allyl Carbohydrate Derivatives. Tetrahedron, 56, 8945 Elsevier
1999 Regioselective Synthesis of Chiral Six-and Seven Membered N-Heterocycles from N-allyl Carbohydrate Nitrones Cyclo-addition: Tuning of Regio-selectivity by N-Substitution. Tetrahedron, 55, 12157 Elsevier
1998 Thiourea: A Novel Cleaving Agent for 1, 3-Dioxolanes. Cited in Chemical & Engineering News 2000, 78, 91 – 117. J. Org. Chem., 64, 5682 American Chemical Society
1997 Expeditious Synthesis of Chiral Six- and Seven- membered Nitrogen Heterocycles from Carbohydrate Amines by N-allyl Nitrone Cycloaddition: Tuning of Regioselectivity by N-Substitution. Tetrahedron Lett. 1997, 38, 8581 Elsevier

Seminar / Conference / Workshop / Refresher / Orientation Etc. Participated

  Seminar/Conference/ workshop Date &Duration Organized by
1 Seventeenth national Symposium on Organic Chemistry (NASOC-XVII): Symposium on Natural Products and Drugs Development September 23-25, 1997 Department of Chemistry, University of Calcutta
2 Biomedical Research in India; perspectives and prospects” on the occasion of Dr. J. C. Ray Birth Centenary Celebration February 27-28, 2000 Indian Institute of Chemical Biology, Kolkata
3 The 67th Annual Meeting of “The Israel Chemical Society”. January 29-30, 2002 Israel Chemical Society, Jerusalem
4 Fifth Asian Federation for Medicinal Chemistry (AFMC) International Medicinal Chemistry Symposium (AIMECS 03) October 14-17, 2003 Asian Federation for Medicinal Chemistry, Kyoto
5 “The Kinki JPS” Conference November 01, 2003 The pharmaceutical Society of Japan, Osaka
6 National Symposium on “Impact of Chemistry on Life and Society” October 1-3, 2004 Department of Chemistry, Tripura University
7 Workshop on Capacity Building 26-30 Dec., 2005 Tripura University
8 Invited speaker in the seminar on “Toxic Chemicals in our environment” August 25, 2006 Department of Chemistry, Ramthakur College, Agartala
9 Workshop on the “Beyond UHPLC: Rapid Separation LC-the Universal solution for fast LC” October 07, 2008 Dionex Corporation, Canada, Ottawa
10 XXth Annual Conference of Physiological Society of India December 12-14, 2008 Department of Human Physiology, Tripura University
11 Annual meeting of Ottawa System Biology: Brain and Mind April 23-24, 2009 Department of System Biology, University of Ottawa, Canada
12 On the Occasion of DST sponsored First INSPIRED programme August 26, 2009 Faculty of Science, Tripura University
13 Regional Seminar on “Recent trends in Chemistry” September 12-13, 2009 Department of Chemistry, Dharmanagar college, Tripura (N)
14 Celebration of “Ottawa Health Research day” November 27, 2009 OHRI, Ottawa, CANADA
15 Statelevel Seminar on ‘Emerging areas & Opportunity of Studies and Research in Science’ August 13-14, 2010 Department of Higher Education, Womens College, Agartala
16 Statelevel Seminar on ‘Frontier areas of Chemistry’ on the occasion of 150th Birth Anniversary of Acharjya P. C. Ray. September 03, 2010 Department of Chemistry, Tripura University.
17 State level seminar-cum awareness programme on ‘Global Climate Changes and Clean Developement mechanism: Issues and Impact’ under NAPCC, Govt. of India; acted as Organizing Secretary September 06, 2010. Department of Chemistry, TU and Sponsored by Department of Scienece, Technology & Environment, Govt. of Tripura
18 International Conference on Emerging Areas of Chemistry- January 12-14, 2011. Department of Chemistry, TU
19 XVth National Conference on Surfactants, Emulsions and Biocolloids- 27-29th December, 2011 Department of Chemistry, TU
20 DST-INSPIRED orientation programme at IISER, Pune, April 13-14, 2012 IISER, Pune, Maharastra
21 National seminar on ‘Green Chemistry &Nanoscience: Theory & Applications’, July 20-21, 2012 Department of Chemistry, MBB College in collabora-tion with NIT, Agartala
22 DST-SERB ‘Group Monitoring Workshop’ 23-24 August, 2013. Dept. of Chemistry, Bangalore University, Bangalore-560 001
23 Science Academies Lecture workshop on ‘FROTIERS IN ADVANCED BIO-CHEMICAL SCIENCE’ February 25-27, 2015 Department of Chemistry, DDM College, Khowai in collaboration with IASc, INSA and NASc
24 REACH-2015 An international symposium on Recent Advances in Chemistry, March 03-05, 2015 Department of Chemistry, North Eastern Hill University, Shillong  
25 UGC Sponsored National Seminar on Recent Trend of Research in Chemistry-A New Horizon of Hopes August 8-9, 2015 Department of Chemistry, Womens College, Agartala
26 DST-FIST Project workshop 29th September, 2015 KIIT, Bhubaneswar, Odisha
27 On the occasion of National Science Day 28th Feb., 2018 Women's College, Agartala
28 DST-FIST Project Monitoring workshop 23rd September, 2018 Indian Academy of Sciences, Bangalore
29 International Conference on Chemistry for Human Development (ICCHD-2020) 09-11 January 2020 Department of Chemistry, University of Calcutta, Kolkata

Membership / Positions in learned academic bodies / Organizations

  1. Life member of Indian Association for the Cultivation of Science, Kolkata 700 032
  2. Life member of Tripura Chemical Society, Agartala, Tripura

Research Projects:

  1. Synthesis of α-amino acid derivatives having Quaternary stereo-center- funded by CSIR, India (Sanction letter no. 01 (2089)/06/EMR-II), November 2006-October 2007, Total amount: Rs. 4,64,500/-, PI
  2. Mammalian Subtilases in Viral Infections: Design, Synthesis and Biochemical Applications of Inhibitors- Associate Investigator under the Mentorship of Dr. Ajoy Basak, Ottawa Health Research Institute, Ottawa, Canada, Funded by Canadian Institute of Health Research (CIHR) under the CANADA-HOPE fellowship program. Total funding: CAD $ 174,000.00 for FOUR years, March 2008 to February 2012 (first two years in OHRI, Ottawa, Canada and last two years in TRIPURA UNIVERSITY.
  3. Chiral Auxilliary Induced Asymmetric Synthesis of α,α-Dialkyl-α-Amino Acid Derivatives – funded by DST under SERC project (2011-2014); total amount ~ Rs. 50 lacs., PI.
  4. Overcoming EGFR resistant Oral Squamous Cell Carcinomas: With traditional healers of Tripura – A Preclinical Study (as Co-PI), DBT, Govt. of India, Rs. 47.10 lacs (2014-2017)
  5. Molecular and cellular studies on normal and diabetic wound healing activities of Parkia javanica, a medicinal plants of Tripura, North East India (as Co-PI), DBT, Govt. of India, Rs. 63.36 lacs (2014-2017)
  6. Synthesis and characterisation of some novel chiral compounds containing anthracene or other aromatic fluorophore, (Principal Investigator), CSIR, Govt. of India Rs. 8.50 lacs (2015-2018)
  7. Studies on the synthesis and Physiochemical characterization of novel multi-substituted imidazole, benzimidazole and carbazole derivatives (Principal Investigator), DST-SERB project, Govt. of India, Rs. 22.352 lacs (2017-2020)

Research Supervisions (Scholar's Name, Topic and Status)

Name of the Scholar Topic Status
Ms. Barnali Deb Studies on the development of sustainable routes for some C-N and C-C bond forming reactions Awarded 2022
Mr. Abhijit Rudra Pal Studies on the Synthesis and Characterization of Novel Coumarin and Some Other Heterocycle Derived Compounds Thesis submitted
Mr. Kamal Das Studies on the Carbon-Heteroatom bond formation reaction towards synthetically useful organic molecules under mild and eco-friendly conditions Registered (4th Semester)
Mr. Sourav Chakraborty Studies on the development of sustainable medium for some Carbon-Carbon bond forming reactions Registered (4th Semester)
Ms. Barnali Das Sustainable strategy towards the development of novel routes for the synthesis of bis-heterocycles and other related compounds 1st Semester
Ms. Jhinuk De Functionalization of amino group by the catalysis of protic ionic liquid and synthesis of some biologically active nitrogen heterocycles Ph. D. Awarded
Mr. Mithun Chakraborty Studies on the development of newer methodology for the synthesis of imidazoles and benzimidazoles under environ-mentally benign condition Ph. D. Awarded
Mr. Jewel Hossain Studies on the development of some greener protocols for the synthesis of highly functionalized heterocyclic molecules Ph. D. Awarded
Ms. Ankita Chakraborty Studies on the development of some greener protocols for the synthesis of highly functionalized heterocyclic molecules Ph. D. Awarded
Co-supervisor: Mr. Rajib Paul, Supervisor: Prof. M. K. Singh Study on the Assessment of Ground Water Quality in Selected Rural Tribal Areas of West Tripura District Awarded December 2021
Co-supervisor: Mr. BishuKarmakar, Supervisor: Prof. M. K. Singh Assessment of Pollutional Load in Water and Air from Some Selected Industrial Areas in West Tripura District Awarded December 2021
Tanusree Debnath With Co-supervisor Dr. S. Debnath Design, synthesis and activity study of HDAC8 inhibitors Registered 2018

Scholarship / Award / Recognitions:

1 National Eligibity test For Research Fellowship Scholarship from UGC 1995 – 2000
2 Post-Doctoral Scholarship Technion–Israel Institute of Technology, ISRAEL 2000-2002
3 Japan Society for Promotion of Science Award (JSPS) JSPS, Govt. of Japan 2002-2004
4 CANADA-HOPE Visiting Scientist Award Canadian Institute of Health Research, Govt. of Canada 2008-2012

Other Information (if any):

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