Department of Molecular Biology and Bioinformatics

Research Interests:

Publications (year wise) :

Research papers in refereed journal having ISSN

1. Radio-attenuated leishmanial parasites as immunoprophylactic agent against experimental mur-ine visceral leishmaniasis. Datta S, Adak R, Chakraborty P, Haldar AK, Bhattacharjee S, Chak-raborty A, Roy S, Manna M. Exp Parasitol. 2012.

1. Leaf extract of Moringa oleifera prevents ionizing radiation-induced oxidative stress in mice. Sinha M, Das DK, Bhattacharjee S, Majumdar S, Dey S. J Med Food. 2011 Oct; 14(10):1167-72. Epub 2011 Aug 23. PubMed PMID: 21861723.
2. Berberine Chloride Mediates Its Anti-Leishmanial Activity via Differential Regulation of the Mitogen Activated Protein Kinase Pathway in Macrophages. Saha P, Bhattacharjee S, Sarkar A, Manna A, Majumder S, Chatterjee M. PLoS One. 2011; 6(4):e18467.
3. Alteration of immune functions and Th1/Th2 cytokine balance in nicotine-induced murine macrophages: Immunomodulatory role of eugenol and N-acetylcysteine. Kar Mahapatra S, Bhattacharjee S, Chakraborty SP, Majumdar S, Roy S. International Immunopharmacology. 2011; 11(4):485-95.

1. Amphotericin B Regulates the Host Immune Response in Visceral Leishmaniasis: Reciprocal Regulation of Protein Kinase C isoforms. Mukherjee A, Gupta G, Bhattacharjee S, Guha SK, Majumder S, Adhikari A, Bhattachrya P, Majumdar SB, Majumdar S. J Infect. 2010; 61(2):173-84.
2. Ara-LAM mediated protection in visceral leishmaniasis through upregulation of TLR-2 signaling: an immunoprophylactic approach. Bhattacharya P, Bhattacharjee S, Gupta G, Majumder S, Adhikari A, Mukherjee A, Bhattacharyya Majumdar S, Saha B, Majumdar S. The Journal of Infectious Diseases. 2010; 202(1):145-55.

1. CXC chemokine mediated protection against visceral leishmaniasis: Involvement of proinflammatory response. Gupta G, Bhattacharjee S, Bhattacharyya S, Bhattacharya P, Adhikari A Mukherjee A, Bhattacharyya Mujumdar S, Majumdar S. The Journal of Infectious Diseases. 2009; 200(8):1300-10.
2. Administration of Anti-IL-10 mAb confers protection against experimental visceral leishmaniasis via induction of Th1 cytokines and nitric oxide. Bhattacharjee S, Gupta G, Bhattacharya P, Adhikari A, Bhattacharya Majumdar S, Majumdar S. " Indian Journal of Experimental Biology. 2009; 47(6):489-97.
3. Quassin Alters the Immunological Patterns of Murine Macrophages Through Generation of Nitric Oxide to Exert Antileishmanial Activity. Bhattacharjee S, Gupta G, Bhattacharya P, Mukherjee A, Bhattacharyya Mujumdar S, Pal A, Majumdar S. The Journal of Antimicrobial Chemotherapy. 2009; 63(2): 317-24.
4. Potentiation of macrophage function by cigarette smoke against Leishmania donovani infection.Maity PC, Bhattacharjee S, Majumdar S, Sil AK. Inflammation Research. 2009; 58(1): 22-29.
5. In Vitro Nicotine-Induced Oxidative Stress in Mice Peritoneal Macrophages: A Dose-Dependent Approach. Kar Mahapatra S, Das S, Bhattacharjee S, Gautam N, Majumdar S, Roy S. Toxicology Mechanisms and Methods. 2009; 19(2): 100 - 108.

1. Anti-inflammatory effect of allylpyrocatechol in LPS-induced macrophages is mediated by suppression of iNOS and COX-2 via the NF-kappaB pathway. Sarkar D, Saha P, Gamre S, Bhattacharjee S, Hariharan C, Ganguly S, Sen R, Mandal G, Chattopadhyay S, Majumdar S, Chatterjee M. International Immunopharmacology. 2008; 8(9):1264-71.
2. Arabinosylated lipoarabinomannan modulates the impaired cell mediated immune response in Mycobacterium tuberculosis H37Rv infected C57BL/6 mice. Majumder N*, Bhattacharjee S*, Dey R, Bhattacharyya Majumdar S, Pal NK, Majumdar S. Microbes Infect. 2008; 10(4): 349-57. [* Both of them equally contributed].
3. A novel approach to regulate experimental visceral leishmaniasis in murine macrophages using CCR5 siRNA. Bhattacharyya S, Dey R, Majumder N, Bhattacharjee S, Majumdar S. Scand J Immunology. 2008; 67(4): 345-53.
4. Restoration of impaired free radical generation and proinflammatory cytokines by MCP-1 in mycobacterial pathogenesis. Majumder N, Bhattacharjee S, Bhattacharyya Majumdar S, Dey R, Guha P, Pal NK, Majumdar S. Scand J Immunol. 2008; 67(4): 329-39.

1. Induction of host protective immune response by chemokines in visceral leishmaniasis:importance of ceramide as atherapeutic target. Bhattacharjee S, Dey R, Bhattacharya P, Mukherjee A, Bhattacharyya Majumdar S, Majumdar S. Perspective in Cytology and Genetics. 2007; 13: 115-124.
2. Immunomodulatory role of arabinosylated lipoarabinomannan on Leishmania donovani infected murine macrophages. Bhattacharjee S, Majumder N, Bhattacharyya P, Bhattacharyya S, Majumdar S. Indian J Biochem Biophys. 2007; 44(5):366-72.
3. Induction of host protective Th1 immune response by chemokines in Leishmania donovani-infected BALB/c mice. Dey R, Majumder N, Bhattacharyya Majumdar S, Bhattacharjee S, Banerjee S, Roy S, Majumdar S. Scand J Immunol. 2007; 66(6): 671-83.
4. Leishmania donovani-induced ceramide as the key mediator of Akt dephosphorylation in murine macrophages: role of protein kinase Czeta and phosphatase. Dey R, Majumder N, Bhattacharjee S, Majumdar SB, Banerjee R, Ganguly S, Das P, Majumdar S. Infect Immun. 2007; 75(5): 2136-42.
5. Ceramide as the chief villain in the perspective of visceral leishmaniasis: its role as the platform for pathogenic establishment. Review. Dey R, Ghosh S, Battacharjee S, Majumder N, Majumdar S. Science and Culture. 2007.73 (5-6).

1. Specific and randomly derived immunoactive peptide mimotopes of mycobacterial antigens. Sharma A, Saha A, Bhattacharjee S, Majumdar S, Das Gupta SK. Clin Vaccine Immunol. 2006; 13(10): 1143-54.

Seminar/ Conference/ Workshop/ Training Program etc. Participated:

1. Oral presentation given at the one day Seminar on "Recent Developments in Molecular Neuroscience" at Indian Institute of Chemical Biology, Kolkata, January 9, 2002, on "Alteration of brain monoamines & EEG wave pattern in rat model of Epilepsy & protection by Moringa oleifera."
2. A poster presentation given at the IMMCON-2005: Indian Immunological Society conference from Nov 24-27, 2005, at PGIMER, Chandigarh, on "Anti-Interleukin 10 antibody as a therapeutic tool against visceral leishmaniasis."
3. Poster presentation at the International Conference on Frontier Researches in Integrative Physiology (ICFRIP) held at Kolkata, from Jan 8-10, 2007 on "Anti-IL-10 mAb confers protection against experimental visceral leishmaniasis through upregulation of Th1 immune response".
4. A poster presentation given at the 33rd Indian Immunology Conference IMMCON 2007 held at All India Institute of Medical Sciences (AIIMS), New Delhi, from Jan 28-31, 2007 on "Immuno-modulatory role Arabinosylated Lipoarabinomannan on Leishmania donovani infected murine macrophages: generation of protective immune response."
5. Participated in the Workshop on Techniques in Cell Biology during March 30, 2007 to April 5, 2007 organized by Centre of Advanced Study, Department of Botany, University of Calcutta.
6. Oral Presentation given at the 95th Indian Science Congress held at Andhra University, Visakhapatnam, from Jan 3-7,2008 on "An ammonium salt of a triterpenoid compound suppress Cox-2 gene expression and can be used as an immunotherapeutic agent against visceral Leishmaniasis in murine model.".
7. A poster presentation given at the International Conference on Perspectives of Cell Signaling and Molecular Medicine at Kolkata, from Nov 27-28, 2008 on "Quassin Alters the Immunological Patterns of Murine Macrophages Through Generation of Nitric Oxide to Exert Antileishmanial Activity."

Membership/Positions in Learned Academic Bodies/Organisations:

• Immunological Society of India.
• Society of Biological Chemists.

Research Projects:

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Research Supervisions:

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Scholarship/Award/Recognitions:

• Prof. A. K. Mukherjee Memorial Gold Medal (2002). From Department of Physiology, Calcutta University.

Other Information (if any):

• Reviewer:Toxicology Mechanisms and Methods. Publisher: Informa Pharmaceutical Science (UK).